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经验公式(希尔记法):
C11H10N4S3
化学文摘社编号:
分子量:
294.42
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
产品名称
Ceefourin 1, ≥95% (HPLC)
SMILES string
CN1C(CSC2=NC3=C(C=CC=C3)S2)=NNC1=S
assay
≥95% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
-10 to -25°C
Quality Level
Biochem/physiol Actions
Ceefourin 1 is a potent and highly selective MRP4 (Multidrug resistance protein 4) inhibitor that exhibits low cellular toxicity and high microsomal and acid stability. Ceefourin 1 inhibits PDAC (pancreatic ductal adenocarcinoma) cell proliferation through MRP4-dependent cAMP extrusion thereby activation of the cAMP/Epac/Rap1 signaling pathway.
Potent and highly selective MRP4 (Multidrug resistance protein 4) inhibitor
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
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