SML3357
Rasarfin
≥98% (HPLC)
别名:
N-(3-Chloro-4-(4-isobutyrylpiperazin-1-yl)phenyl)benzofuran-2-carboxamide, N-[3-Chloro-4-[4-(2-methyl-1-oxopropyl)-1-piperazinyl]phenyl]-2-benzofurancarboxamide
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关于此项目
Quality Level
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear (Warmed)
storage temp.
2-8°C
SMILES string
O=C(C1=CC2=C(C=CC=C2)O1)NC3=CC=C(N4CCN(CC4)C(C(C)C)=O)C(Cl)=C3
InChI key
SRZCCUYFJZQLGE-UHFFFAOYSA-N
Biochem/physiol Actions
Dual Ras and ARF6 inhibitor that inhibits both receptor internalization and signaling
Rasarfin is a dual Ras and ARF6 inhibitor that inhibits both receptor internalization and signaling. It blocks agonist-mediated internalization of AT1R and other GPCRs. Rasarfin potently inhibits agonist induced ERK1/2 signaling by GPCRs, and MAPK and Akt signaling by EGFR. It prevents cancer cell proliferation.
存储类别
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| SML3357-25MG | 04065268918180 |
| SML3357-5MG | 04065268918197 |