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SML3387

Rilpivirine

Name: Rilpivirine
Brand: SIGMA

≥98% (HPLC), NNRTI inhibitor, powder

别名:

4-[[4-[[4-[(1E)-2-Cyanoethenyl]-2,6-dimethylphenyl]amino]-2-pyrimidinyl]amino]benzonitrile, R 278474, TMC 278

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关于此项目

经验公式（希尔记法）:

C₂₂H₁₈N₆

化学文摘社编号:

500287-72-9

分子量:

366.42

NACRES:

NA.77

UNSPSC Code:

51111800

MDL number:

MFCD11046372

Assay:

≥98% (HPLC)

Form:

powder

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属性

产品名称

Rilpivirine, ≥98% (HPLC)

Quality Segment

100

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

2-8°C

SMILES string

CC1=CC(=CC(=C1NC2=NC(=NC=C2)NC3=CC=C(C=C3)C#N)C)/C=C/C#N

InChI

1S/C22H18N6/c1-15-12-18(4-3-10-23)13-16(2)21(15)27-20-9-11-25-22(28-20)26-19-7-5-17(14-24)6-8-19/h3-9,11-13H,1-2H3,(H2,25,26,27,28)/b4-3+

InChI key

YIBOMRUWOWDFLG-ONEGZZNKSA-N

说明

Biochem/physiol Actions

Nonnucleoside reverse transcriptase inhibitor (NNRTI); anti-retroviral

Rilpivirine is a next generation nonnucleoside reverse transcriptase inhibitor (NNRTI), It has been shown to be active against many HIV strains with mutations that confer resistance to the first-generation NNRTIs.

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存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c