SML3403
HSip-1 DA trifluoroacetate hydrate
≥95% (HPLC)
别名:
Cyclen-AF-Cu DA trifluoroacetate hydrate, HSip 1 DA, HSip-1 diacetate trifluoroacetate hydrate, HSip1 DA, Hydrogen Sulfide imaging probe-1 DA, [N-(3′,6′-bis(Acetyloxy)-3-oxospiro[isobenzofuran-1(3H),9′-[9H]xanthen]-5-yl)-1,4,7,10-tetraazacyclododecane-1-acetamide-κN1,κN4,κN7,κN10]-copper(2+) trifluoroacetate hydrate
SMILES string
O=C1OC2(C3=CC=C(NC(C[N]45CCN6CCN7CCN([Cu@+2]765)CC4)=O)C=C13)C8=CC=C(C=C8OC9=CC(OC(C)=O)=CC=C92)OC(C)=O.[y H2O]
assay
≥95% (HPLC)
form
powder
mol wt
707.23 g/mol
storage condition
protect from light
color
, Light Blue to Green Blue
solubility
H2O: 2 mg/mL, clear
storage temp.
-10 to -25°C
Quality Level
Biochem/physiol Actions
Cell-permeable HSip-1 diacetate precursor. Sensitive and selective intracellular hydrogen sulfide (H2S) fluorescent probe.
HSip-1 DA corresponds to the cell-permeable diacetate ester precursor of the sensitive hydrogen sulfide (H2S)-selective fluorescent turn-on probe HSip-1 (Cyclen-AF-Cu; Hydrogen Sulfide imaging probe-1). Once entering cells, HSip-1 DA is hydrolyzed by esterases to form HSip-1, allowing the selective detection of intracellular H2S by fluorescence (Ex 470-490 nm, Em 510-550 nm). For intracellular loading, incubate cells with 5-30 μM Hsip-1 DA in DMEM at 37 °C for 30 min before removing unincorporated probe by washing with HBSS.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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