SML3408
EG00229 trifluoroacetate
≥98% (HPLC)
别名:
N2-[[3-[(2,1,3-Benzothiadiazol-4-ylsulfonyl)amino]-2-thienyl]carbonyl]-L-arginine trifluoroacetate
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关于此项目
Assay:
≥98% (HPLC)
Form:
powder
Storage condition:
desiccated
Quality Segment
assay
≥98% (HPLC)
form
powder
storage condition
desiccated
color
white to beige
storage temp.
−20°C
SMILES string
FC(F)(F)C(=O)O.[S](=O)(=O)(Nc3c([s]cc3)C(=O)N[C@@H](CCCN=C(N)N)C(=O)O)c1c2n[s]nc2ccc1
InChI
1S/C17H19N7O5S3.C2HF3O2/c18-17(19)20-7-2-4-11(16(26)27)21-15(25)14-10(6-8-30-14)24-32(28,29)12-5-1-3-9-13(12)23-31-22-9;3-2(4,5)1(6)7/h1,3,5-6,8,11,24H,2,4,7H2,(H,21,25)(H,26,27)(H4,18,19,20);(H,6,7)/t11-;/m0./s1
InChI key
ZYQBITUOSRZDTG-MERQFXBCSA-N
Biochem/physiol Actions
Antagonist of the VEGF-A receptor neuropilin 1 (NRP1)
EG00229 trifluoroacetate is an antagonist of the VEGF-A receptor neuropilin 1 (NRP1), which decreases viability of A549 lung carcinoma cells. EG00229 trifluoroacetate impairs VEGFA induced migration of HUV-EC-C endothelial cells.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable