SML3411
LY2828360
≥98% (HPLC)
别名:
8-(2-Chlorophenyl)-2-methyl-6-(4-methyl-1-piperazinyl)-9-(tetrahydro-2H-pyran-4-yl)-9H-purine, LY 2828360
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关于此项目
经验公式（希尔记法）:
C22H27ClN6O
化学文摘社编号:
分子量:
426.94
UNSPSC Code:
41121800
NACRES:
NA.77
MDL number:
SMILES string
Clc1c(cccc1)c2[n](c4nc(nc(c4n2)N5CCN(CC5)C)C)C3CCOCC3
InChI
1S/C22H27ClN6O/c1-15-24-21(28-11-9-27(2)10-12-28)19-22(25-15)29(16-7-13-30-14-8-16)20(26-19)17-5-3-4-6-18(17)23/h3-6,16H,7-14H2,1-2H3
InChI key
UCMNDPDJRSEZPL-UHFFFAOYSA-N
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear (Warmed)
storage temp.
-10 to -25°C
Quality Level
Biochem/physiol Actions
LY2828360 is a potent and selective slowly acting G protein-biased CB2 cannabinoid agonist that inhibits cAMP accumulation and activates ERK1/2 signaling while failing to recruit arrestin. LY2828360 suppress chemotherapy-induced neuropathic pain created by paclitaxel without producing tolerance in mice.
Potent and selective slowly acting G protein-biased CB2 cannabinoid agonist
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
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