SML3430
Benvitimod
≥98% (HPLC), AHR immunomodulator, powder
别名:
(E)-2-Isopropyl-5-styrylbenzene-1,3-diol, 3,5-Dihydroxy-4-isopropyl-trans-stilbene, 3,5-Dihydroxy-4-isopropylstilbene, GSK-2894512, Tapinarof, WBI 1001
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关于此项目
经验公式（希尔记法）:
C17H18O2
化学文摘社编号:
分子量:
254.32
NACRES:
NA.77
UNSPSC Code:
41121706
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
产品名称
Benvitimod, ≥98% (HPLC)
Quality Segment
assay
≥98% (HPLC)
form
powder
color
, White to Very dark grey
solubility
DMSO: 2 mg/mL, clear
storage temp.
−20°C
SMILES string
CC(C1=C(C=C(C=C1O)/C=C/C2=CC=CC=C2)O)C
InChI
1S/C17H18O2/c1-12(2)17-15(18)10-14(11-16(17)19)9-8-13-6-4-3-5-7-13/h3-12,18-19H,1-2H3/b9-8+
InChI key
ZISJNXNHJRQYJO-CMDGGOBGSA-N
Biochem/physiol Actions
Aryl hydrocarbon receptor (AHR) immunomodulator that inhibits skin inflammation and enhances skin barrier function.
Benvitimod (Tapinarof) is an aryl hydrocarbon receptor (AHR) immunomodulator that inhibits skin inflammation and enhances skin barrier function. Benvitimod is a metabolite, similar to resveratrol, produced by bacterial symbionts of entomopathogenic nematodes. It induces downregulation of inflammatory cytokines such as IL-17A, IL-17F, IL-19, IL-22, IL-23, and IL-1. Benvitimod also induces the expression of skin barrier genes related to keratinocyte differentiation.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable