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经验公式(希尔记法):
C27H34N4O5
化学文摘社编号:
分子量:
494.58
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
SMILES string
N4(CCC(CC4)C(=O)c5ccc(cc5)OC)CC(=O)N(CC3CC3)Cc1[nH][c](c2c(n1)CCOC2)=O
InChI
1S/C27H34N4O5/c1-35-21-6-4-19(5-7-21)26(33)20-8-11-30(12-9-20)16-25(32)31(14-18-2-3-18)15-24-28-23-10-13-36-17-22(23)27(34)29-24/h4-7,18,20H,2-3,8-17H2,1H3,(H,28,29,34)
InChI key
DYGBNAYFDZEYBA-UHFFFAOYSA-N
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
2-8°C
Quality Level
Biochem/physiol Actions
NVP-TNKS656 is an orally active, highly potent and selective tankyrase inhibitor. NVP-TNKS656 is a potent antagonist of Wnt pathway that reverts resistance to PI3K and AKT inhibitors in treatment of colorectal cancer.
orally active, highly potent and selective tankyrase inhibitor
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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