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Merck
CN

SML3464

Gossypetin

≥98% (HPLC), MKK3 and MKK6 protein kinases inhibitor, powder

别名:

2-(3,4-Dihydroxyphenyl)-3,5,7,8-tetrahydroxy-4H-1-benzopyran-4-one, 8-Hydroxyquercetin, Articulatidin, Equisporol

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关于此项目

经验公式(希尔记法):
C15H10O8
化学文摘社编号:
分子量:
318.24
NACRES:
NA.77
UNSPSC Code:
12352200
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
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产品名称

Gossypetin, ≥98% (HPLC)

Quality Segment

assay

≥98% (HPLC)

form

powder

color

, light green to yellow

solubility

DMSO: 2 mg/mL, clear

storage temp.

-10 to -25°C

SMILES string

OC1=CC(O)=C2C(C(O)=C(OC2=C1O)C3=CC=C(C(O)=C3)O)=O

InChI

1S/C15H10O8/c16-6-2-1-5(3-7(6)17)14-13(22)12(21)10-8(18)4-9(19)11(20)15(10)23-14/h1-4,16-20,22H

InChI key

YRRAGUMVDQQZIY-UHFFFAOYSA-N

Biochem/physiol Actions

Antioxidant, antibacterial, anticancer; potent inhibitor of MKK3 and MKK6 protein kinases
Gossypetin is a hexahydroxylated flavonoid found in the flowers and the calyx of Hibiscus, which exhibits numerous pharmacological effects, including antioxidant, antibacterial and anticancer activities. It induces apoptosis and autophagic cell death in prostate cancer cells. Gossypetin is a potent inhibitor of MKK3 and MKK6 protein kinases that suppresses esophageal cancer growth.


存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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