SML3494
β-Benzamide adenine dinucleotide sodium salt
≥95% (HPLC), IMPDH inhibitor, powder
别名:
Adenosine 5′-(trihydrogen diphosphate) P′→5′-ester with 3-β-D-ribofuranosylbenzamide sodium salt, BAD, benzamide adenine dinucleotide sodium salt
产品名称
β-Benzamide adenine dinucleotide sodium salt, ≥95% (HPLC)
SMILES string
O[C@@H]1[C@H](O)[C@@H](COP(OP(OC[C@@H]2[C@@H](O)[C@@H](O)[C@H](N(C=N3)C4=C3C(N)=NC=N4)O2)(O[Na])=O)(O[Na])=O)O[C@H]1C5=CC(C(N)=O)=CC=C5
assay
≥95% (HPLC)
form
powder
storage condition
desiccated
color
white to beige
storage temp.
-10 to -25°C
Quality Level
Biochem/physiol Actions
β-Benzamide adenine dinucleotide (BAD), an analogue of nicotinamide adenine dinucleotide (β-NAD+), is an active metabolite of benzamide riboside and a potent inhibitor of inosine 5′-monophosphate dehydrogenase (IMPDH). Also, β-Benzamide adenine dinucleotide is a non-hydrolysable substrate/inhibitor of NADases and PARP enzymes. A higher concentration (Ki = 90 μM) it inhibits human NAD kinase.
Analogue of nicotinamide adenine dinucleotide (β-NAD+); inhibitor of inosine 5′-monophosphate dehydrogenase (IMPDH)
存储类别
11 - Combustible Solids
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