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Merck
CN

SML3501

Dehydrocorydaline

≥98% (HPLC)

别名:

13-Methylpalmatine, 5,6-Dihydro-2,3,9,10-tetramethoxy-13-methyldibenzo[a,g]quinolizinium

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关于此项目

经验公式(希尔记法):
C22H24NO4
化学文摘社编号:
分子量:
366.43
UNSPSC Code:
41115709
NACRES:
NA.77
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
Quality level:
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InChI

1S/C22H24NO4/c1-13-15-6-7-18(24-2)22(27-5)17(15)12-23-9-8-14-10-19(25-3)20(26-4)11-16(14)21(13)23/h6-7,10-12H,8-9H2,1-5H3/q+1

SMILES string

CC1=C2[N+](CCC3=C2C=C(OC)C(OC)=C3)=CC4=C(OC)C(OC)=CC=C41

InChI key

RFKQJTRWODZPHF-UHFFFAOYSA-N

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

-10 to -25°C

Quality Level

Biochem/physiol Actions

Alkaloidal isolated from Rhizoma corydalis that exhibits anti-inflammatory, antinociceptive and anti-tumor effects
Dehydrocorydaline is an alkaloidal isolated from Rhizoma corydalis that exhibits anti-inflammatory, antinociceptive and anti-tumor effects. Dehydrocorydaline attenuates bone cancer pain through suppression M1 phenotype and upregulation M2 phenotype of microglia in the spinal cord.

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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分析证书(COA)

Lot/Batch Number

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Dehydrocorydaline attenuates bone cancer pain by shifting microglial M1/M2 polarization toward the M2 phenotype.
Huo W, Zhang Y, Liu Y, Lei Y, Sun R, Zhang W, Huang Y, Mao Y, Wang C, Ma Z, Gu X.
Molecular Pain (2018)
Zhi-Yu Yin et al.
Scientific reports, 6, 27129-27129 (2016-06-09)
Dehydrocorydaline (DHC) is an alkaloidal component isolated from Rhizoma corydalis. Previous studies have shown that DHC has anti-inflammatory and anti-tumor effects and that it can protect the cardiovascular system. However, there are few studies of the antinociceptive effects of DHC

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