SML3514
Corylin
≥98% (HPLC)
别名:
3-(2,2-Dimethyl-2H-1-benzopyran-6-yl)-7-hydroxy-4H-1-benzopyran-4-one
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关于此项目
经验公式（希尔记法）:
C20H16O4
化学文摘社编号:
分子量:
320.34
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
产品名称
Corylin, ≥98% (HPLC)
InChI key
PWAACAMQKVIVPZ-UHFFFAOYSA-N
SMILES string
O=C1C2=CC=C(C=C2OC=C1C3=CC4=C(C=C3)OC(C)(C)C=C4)O
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
2-8°C
Quality Level
Biochem/physiol Actions
Corylin is a flavonoid isolated from fruit and seed of medical herb Psoralea corylifolia that extend the replicative lifespan in yeast by targeting the Gtr1 protein. Also, Corylin extends lifespan in mice fed a high-fat diet. Corylin exhibits numerous pharmacological effects such as antioxidant properties, anti-inflammatory effects, osteoblastic proliferation-stimulating activity, insulin resistance amelioration.
Extend the replicative lifespan in yeast by targeting the Gtr1 protein
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
I-Chen Chen et al.
Pharmaceuticals (Basel, Switzerland), 14(10) (2021-10-24)
Acute lung injury (ALI) is a high mortality disease with acute inflammation. Corylin is a compound isolated from the whole plant of Psoralea corylifolia L. and has been reported to have anti-inflammatory activities. Herein, we investigated the therapeutic potential of
Zi-Yu Chang et al.
International journal of molecular sciences, 23(5) (2022-03-11)
Inflammatory bowel disease (IBD) involves chronic inflammation, loss of epithelial integrity, and gastrointestinal microbiota dysbiosis, resulting in the development of a colon cancer known as colitis-associated colorectal cancer (CAC). In this study, we evaluated the effects of corylin in a
Tong-Hong Wang et al.
Nature communications, 13(1), 1238-1238 (2022-03-11)
In the long history of traditional Chinese medicine, single herbs and complex formulas have been suggested to increase lifespan. However, the identification of single molecules responsible for lifespan extension has been challenging. Here, we collected a list of traditional Chinese
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