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Merck
CN

SML3544

Ginsenoside Ro

≥94% (HPLC)

别名:

(3β)-28-(β-D-Glucopyranosyloxy)-28-oxoolean-12-en-3-yl 2-O-β-D-glucopyranosyl-β-D-glucopyranosiduronic acid, Chikusetsusaponin 5, Polysciasaponin P3

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关于此项目

经验公式（希尔记法）:
C48H76O19
化学文摘社编号:
34367-04-9
分子量:
957.11
UNSPSC Code:
12352200
NACRES:
NA.77

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产品名称

Ginsenoside Ro, ≥94% (HPLC)

SMILES string

O1[C@H]([C@@H]([C@H]([C@@H]([C@H]1CO)O)O)O)O[C@H]2[C@@H](O[C@@H]([C@H]([C@@H]2O)O)C(=O)O)O[C@@H]3C([C@H]4[C@@]([C@@H]5[C@]([C@@]6(CC[C@@]8([C@@H](CC(CC8)(C)C)C6=CC5)C(=O)O[C@@H]7O[C@@H]([C@H]([C@@H]([C@H]7O)O)O)CO)C)(CC4)C)(CC3)C)(C)C

InChI

1S/C48H76O19/c1-43(2)14-16-48(42(61)67-40-35(58)31(54)29(52)24(20-50)63-40)17-15-46(6)21(22(48)18-43)8-9-26-45(5)12-11-27(44(3,4)25(45)10-13-47(26,46)7)64-41-37(33(56)32(55)36(65-41)38(59)60)66-39-34(57)30(53)28(51)23(19-49)62-39/h8,22-37,39-41,49-58H,9-20H2,1-7H3,(H,59,60)/t22-,23+,24+,25-,26+,27-,28+,29+,30-,31-,32-,33-,34+,35+,36-,37+,39-,40-,41+,45-,46+,47+,48-/m0/s1

InChI key

NFZYDZXHKFHPGA-QQHDHSITSA-N

assay

≥94% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

-10 to -25°C

Quality Level

100

Biochem/physiol Actions

TGR5 activator; key constituent of ginseng that exhibits varies health beneficial activities including antitumor, anti-inflammatory, and antioxidant
Ginsenoside Ro is a key constituent of ginseng that exhibits varies health beneficial activities including antitumor, anti-inflammatory, and antioxidant. Ginsenoside Ro ameliorates obesity and insulin resistance in high fat diet-induced obese (DIO) mice without affecting food intake through activation of G protein-coupled bile acid receptor 5 (TGR5).

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302

Hazard Classifications

Acute Tox. 4 Oral

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
0000219641
0000219642
0000202701
0000202701
0000219642

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Ginsenoside Ro Ameliorates High-Fat Diet-Induced Obesity and Insulin Resistance in Mice via Activation of the G Protein-Coupled Bile Acid Receptor 5 Pathway
Journal of Pharmacology and Experimental Therapeutics, 377, 441-451 (2021)

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