SML3547
8RK59
≥98% (HPLC)
别名:
(S)-1-Xyano-N-(5-(2-(4-(4-(5,5-difluoro-1,3,7,9-tetramethyl-5H-4λ4,5λ4-dipyrrolo[1,2-c:2′,1′-f][1,3,2]diazaborinin-10-yl)butyl)-1H-1,2,3-triazol-1-yl)acetyl)-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridin-2-yl)pyrrolidine-3-carboxamide
SMILES string
O=C([C@H]1CCN(C#N)C1)NC2=NC3=C(S2)CN(C(CN4N=NC(CCCCC(C5=C(C)C=C(C)N5[B-]6(F)F)=C7[N+]6=C(C)C=C7C)=C4)=O)CC3
assay
≥98% (HPLC)
form
powder
color
, Faint orange to red
solubility
DMSO: 2 mg/mL, clear
storage temp.
2-8°C
Quality Level
Biochem/physiol Actions
8RK59 is a cellularly active covalent fluorescent probe that targets selectively active UCHL1 (ubiquitin carboxy-terminal hydrolase L1). 8RK59 selectively and spatiotemporally report UCHL1 activity in zebrafish embryos.
Cellularly active covalent fluorescent probe that targets selectively active UCHL1
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Raymond Kooij et al.
Journal of the American Chemical Society, 142(39), 16825-16841 (2020-09-05)
Many reagents have emerged to study the function of specific enzymes in vitro. On the other hand, target specific reagents are scarce or need improvement, allowing investigations of the function of individual enzymes in their native cellular context. Here we
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