SML3555
Pirmenol
≥98% (HPLC)
别名:
CL-845, cis-(±)-α-[3-(2,6-Dimethyl-1-piperidinyl)propyl]-α-phenyl-2-pyridinemethanol, rel-α-[3-[(2R,6S)-2,6-Ddimethyl-1-piperidinyl]propyl]-α-phenyl-2-pyridinemethanol
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关于此项目
经验公式（希尔记法）:
C22H30N2O
化学文摘社编号:
分子量:
338.49
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
InChI
1S/C22H30N2O/c1-18-10-8-11-19(2)24(18)17-9-15-22(25,20-12-4-3-5-13-20)21-14-6-7-16-23-21/h3-7,12-14,16,18-19,25H,8-11,15,17H2,1-2H3/t18-,19+,22?
SMILES string
OC(C1=CC=CC=C1)(C2=NC=CC=C2)CCCN3[C@@H](C)CCC[C@H]3C
InChI key
APUDBKTWDCXQJA-QIDMFYOTSA-N
assay
≥98% (HPLC)
form
powder
color
, White to v. dark grey
solubility
DMSO: 2 mg/mL, clear
storage temp.
2-8°C
Quality Level
Biochem/physiol Actions
Antiarrhythmic agent class Ia
Pirmenol is an antiarrhythmic agent class Ia that exhibit long half-life and low toxicities. Pirmenol suppresses premature ventricular contractions in human studies.
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Pirmenol inhibits muscarinic acetylcholine receptor-operated K+ current in the guinea pig heart.
Watanabe Y, Hara Y, Tamagawa M, Nakaya H.
European Journal of Pharmacology (1997)
CL-845 (pirmenol hydrochloride): a new orally effective long-acting antiarrhythmic agent
Steffe TJ, Mertz TE, Hastings SG, Potoczak RE, Kaplan HR.
Journal of Pharmacology and Experimental Therapeutics (1980)
Pirmenol: an antiarrhythmic drug with unique electrocardiographic features--a double-blind placebo-controlled comparison with quinidine
Salerno DM, Fifield J, Farmer C, Hodges M.
Clinical Cardiology (1991)
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