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SML3560

MU380

≥98% (HPLC)

别名:

(R)-6-bromo-5-(piperidin-3-yl)-3-(1-(trifluoromethyl)-1H-pyrazol-4-yl)pyrazolo[1,5-a]pyrimidin-7-amine; 6-Bromo-5-(3R)-3-piperidinyl-3-[1-(trifluoromethyl)-1H-pyrazol-4-yl]-pyrazolo[1,5-a]pyrimidin-7-amine

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关于此项目

经验公式（希尔记法）:
C15H15BrF3N7
化学文摘社编号:
2109805-78-7
分子量:
430.23
UNSPSC Code:
12352200
NACRES:
NA.21
Assay:
≥98% (HPLC)
Form:
powder
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Quality Segment

100

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

2-8°C

SMILES string

NC1=C(C([C@@]2([H])CNCCC2)=NC3=C(C=NN13)C4=CN(N=C4)C(F)(F)F)Br

Biochem/physiol Actions

MU380 is a metabolically stable analog of CHK1 inhibitor SCH900776 (MK8776) does not undergo in vivo N-dealkylation. MU380 is a potent and selective CHK1 inhibitor, which potently sensitizes multiple cancer cell lines to DNA antimetabolites including hydroxyurea, cytarabine and gemcitabine.
Metabolically stable, potent and selective CHK1 inhibitor

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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