SML3564
ML382
≥98% (HPLC)
别名:
VU0485891, 2-(Cyclopropanesulfonamido)-N-(2-ethoxyphenyl)benzamide
登录 查看组织和合同定价。
选择尺寸
关于此项目
经验公式（希尔记法）:
C18H20N2O4S
化学文摘社编号:
分子量:
360.43
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
InChI key
RCSLEKLNDJJJLF-UHFFFAOYSA-N
SMILES string
O=C(C1=C(C=CC=C1)NS(C2CC2)(=O)=O)NC3=C(C=CC=C3)OCC
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
2-8°C
Quality Level
Biochem/physiol Actions
ML382 is a positive allosteric modulator of Mas-related G-protein-coupled receptor X1 (MrgprX1, MrgX1, SNSR4), a G-protein coupled receptor (GPCR) selectively expressed in dorsal root ganglion (DRG) neurons. MrgX1 is believed to be a functional ortholog of mouse MrgC11, which has been shown to be involved in itch and pain. ML382 is selective for MrgX1 over MrgX2, MrgC11 and a panel of 68 other GPCRs, ion channels and transporters, with an EC50 value of 190 nm with an Emax value of 148% in the presence of the known ligand BAM8-22.
MrgX1 (SNSR4) positive allosteric modulator
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Discovery and characterization of 2-(cyclopropanesulfonamido)-N-(2-ethoxyphenyl)benzamide, ML382: a potent and selective positive allosteric modulator of MrgX1
ChemMedChem, 10, 57-61 (2015)
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持