SML3587
SCH 900776
≥98% (HPLC)
别名:
6-Bromo-3-(1-methyl-1H-pyrazol-4-yl)-5-(3R)-3-piperidinyl-pyrazolo[1,5-a]pyrimidin-7-amine
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选择尺寸
关于此项目
经验公式（希尔记法）:
C15H18BrN7
化学文摘社编号:
分子量:
376.25
UNSPSC Code:
12352200
NACRES:
NA.21
MDL number:
InChI
1S/C15H18BrN7/c1-22-8-10(6-19-22)11-7-20-23-14(17)12(16)13(21-15(11)23)9-3-2-4-18-5-9/h6-9,18H,2-5,17H2,1H3/t9-/m1/s1
SMILES string
NC1=C(Br)C([C@H]2CNCCC2)=NC3=C(C4=CN(C)N=C4)C=NN13
InChI key
GMIZZEXBPRLVIV-SECBINFHSA-N
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
-10 to -25°C
Quality Level
Biochem/physiol Actions
Highly potent and selective CHK1 inhibitor
SCH 900776 is a highly potent and selective CHK1 inhibitor that interacts synergistically with antimetabolites and other agents to induce cancer cell death.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Targeting the replication checkpoint using SCH 900776, a potent and functionally selective CHK1 inhibitor identified via high content screening
Molecular Cancer Therapeutics, 10, 591-602 (2011)
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