SML3602
Pipobroman
≥98% (HPLC)
别名:
1,1′-(1,4-Piperazinediyl)bis[3-bromo-1-propanone, 1,4-bis(3-Bromo-1-oxopropyl)-piperazine, N,N-Bis-(3-bromopropionyl)-piperazine, NSC-25154
质量水平
方案
≥98% (HPLC)
表单
powder
颜色
white to beige
溶解性
DMSO: 2 mg/mL, clear
储存温度
-10 to -25°C
SMILES字符串
BrCCC(=O)N1CCN(CC1)C(=O)CCBr
InChI
1S/C10H16Br2N2O2/c11-3-1-9(15)13-5-7-14(8-6-13)10(16)2-4-12/h1-8H2
InChI key
NJBFOOCLYDNZJN-UHFFFAOYSA-N
相关类别
生化/生理作用
Anti-cancer drug, cytostatic alkylating agent
Pipobroman is an alkylating agent that is used as anti-cancer drug. It also has clinical activity in polycythemia vera and thrombocythemia.
警示用语：
Danger
危险声明
危险分类
Acute Tox. 3 Oral
储存分类代码
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
此项目有
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
Giovanni Fazio et al.
Journal of thrombosis and thrombolysis, 35(2), 282-285 (2012-07-31)
Polycythemia vera (PV) is a chronic myeloproliferative disorder characterized by an abnormal increase in red blood cells. The involvement of the heart during the course of the illness represents a common cause of morbidity and it is linked to an
Jean-Jacques Kiladjian et al.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 29(29), 3907-3913 (2011-09-14)
The overall impact of hydroxyurea (HU) or pipobroman treatments on the long-term outcome of patients with polycythemia vera (PV) has not been assessed in randomized studies. We report final analyses from the French Polycythemia Study Group (FPSG) study, which randomly
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