SML3611
Rubusoside
≥95% (HPLC)
别名:
(4α)-13-(β-D-Glucopyranosyloxy)-kaur-16-en-18-oic acid β-D-glucopyranosyl ester
InChI
1S/C32H50O13/c1-15-11-31-9-5-18-29(2,7-4-8-30(18,3)28(41)44-26-24(39)22(37)20(35)16(12-33)42-26)19(31)6-10-32(15,14-31)45-27-25(40)23(38)21(36)17(13-34)43-27/h16-27,33-40H,1,4-14H2,2-3H3/t16-,17-,18+,19+,20-,21-,22+,23+,24-,25-,26+,27+,29-,30-,31-,32+/m1/
InChI key
YWPVROCHNBYFTP-OSHKXICASA-N
SMILES string
C=C1[C@@]2(O[C@H]3[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O3)C[C@]4(C1)CC[C@]5([H])[C@](C)(C(O[C@H]6[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O6)=O)CCC[C@@]5(C)[C@]4([H])CC2
assay
≥95% (HPLC)
form
powder
optical activity
[α]/D -37 to -47°, c = 0.5 in methanol
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
-10 to -25°C
Quality Level
Biochem/physiol Actions
Natural next generation sugar substitute; exhibits antiangiogenic and antiallergic properties
Rubusoside is a natural next generation sugar substitute isolated from Rubus suavissimus S. Lee. Rubusoside exhibits antiangiogenic and antiallergic properties. It can be used as a solubilizing agent for assorted biologically active agents.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Rubusoside alleviates the ovalbumin-induced mice allergic asthma by modulating the NF-κB activation.
Chengqiang Wang et al.
Journal of food biochemistry, 44(5), e13187-e13187 (2020-03-19)
The anti-inflammatory and anti-asthmatic effects of rubusoside (Rbs) were investigated in the ovalbumin (OVA)-induced asthmatic mice, followed by effective attenuation of Rbs treatment on the airway hyperresponsiveness and reduction of inflammatory cells inside the bronchoalveolar lavage fluid (BALF). The mitigation
Sachin K Khiste et al.
Molecular cancer therapeutics, 19(2), 564-574 (2019-10-28)
Ceramide (Cer) is an active cellular sphingolipid that can induce apoptosis or proliferation-arrest of cancer cells. Nanoparticle-based delivery offers an effective approach for overcoming bioavailability and biopharmaceutics issues attributable to the pronounced hydrophobicity of Cer. Missense mutations of the protein
Chunru Guan et al.
Applied and environmental microbiology, 86(16) (2020-06-07)
Dental caries is a biofilm-mediated disease in which Streptococcus mutans is the main pathogenic microorganism, and its incidence is closely related to sucrose. Rubusoside is a natural nonnutritive sweetener isolated from Rubus suavissimus S. Lee. This study was designed to
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