SML3616
Kazinol U
≥95% (HPLC)
别名:
(+)-Kazinol U, 4-[(2S)-3,4-Dihydro-7-hydroxy-2H-1-benzopyran-2-yl]-3-(3-methyl-2-buten-1-yl)-1,2-benzenediol
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关于此项目
经验公式（希尔记法）:
C20H22O4
化学文摘社编号:
分子量:
326.39
UNSPSC Code:
12352200
NACRES:
NA.21
MDL number:
Assay:
≥95% (HPLC)
Form:
powder
Quality Segment
assay
≥95% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
-10 to -25°C
Biochem/physiol Actions
Anti-melanogenic in mouse and human melanoma cells through the induction of AMPK and MAPK phosphorylation
Kazinol U is prenylated flavan isolated from an extract of Broussonetia kazinoki Sieb (paper mulberry) that exhibits anti-melanogenic activity in mouse and human melanoma cells through the induction of AMPK and MAPK phosphorylation. Kazinol U inhibits tyrosinase activity and melanin synthesis through the reduction of MITF expression. It suppresses melanogenesis in a zebrafish model. Kazinol U displays phytoestrogenic and anti-inflammatory activities. Kazinol U exhibits cytoprotective activities against cytokine-induced apoptotic cell death.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable