跳转至内容
Merck
CN

SML3638

Ceftobiprole

≥95% (HPLC), Cell wall synthesis inhibitor, powder

别名:

(6R,7R)-7-[[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-ylidene)- 2-nitroso-1-oxoethyl]amino]-8-oxo-3-[(E)-[2-oxo-1-[(3R)- 3-pyrrolidinyl]-3-pyrrolidinylidene]methyl]-5-thia-1- azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, BAL 9141, BAL 9141-000, Ro 63-9141

登录 查看组织和合同定价。

选择尺寸

关于此项目

经验公式（希尔记法）:
C20H22N8O6S2
化学文摘社编号:
209467-52-7
分子量:
534.57
UNSPSC Code:
51111800
NACRES:
NA.25
MDL number:
MFCD25976436

主要文件

查看所有文档
技术服务
需要帮助？我们经验丰富的科学家团队随时乐意为您服务。
让我们为您提供帮助
技术服务
需要帮助？我们经验丰富的科学家团队随时乐意为您服务。
让我们为您提供帮助

产品名称

Ceftobiprole, ≥95% (HPLC)

SMILES string

[s]1nc(nc1N)C(N=O)C(=O)N[C@H]2[C@H]3SCC(=C(N3C2=O)C(=O)O)\C=C4/CCN(C/4=O)[C@H]5CNCC5

InChI

1S/C20H22N8O6S2/c21-20-24-14(26-36-20)11(25-34)15(29)23-12-17(31)28-13(19(32)33)9(7-35-18(12)28)5-8-2-4-27(16(8)30)10-1-3-22-6-10/h5,10-12,18,22H,1-4,6-7H2,(H,23,29)(H,32,33)(H2,21,24,26)/b8-5+/t10-,11?,12-,18-/m1/s1

InChI key

XLHWFEHWWUCKOL-ADPMQJGOSA-N

assay

≥95% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear (Acidified)

storage temp.

-10 to -25°C

Quality Level

100

相关类别

Biochem/physiol Actions

Broad-spectrum cephalosporin active against MRSA
Ceftobiprole is a fifth generation broad spectrum cephalosporin that is active against many resistant bacterial strains including methicillin-resistant Staphylococcus aureus (MRSA). Ceftobiprole inhabits PBP1 (penicillin-binding protein 1), PBP2 and ß-lactam resistance determinant PBP2a.

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

涉药品监管产品
此项目有

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
0000503815
0000503814
0000503814
0000503815
0000418269

没有发现合适的版本？

如果您需要特殊版本，可通过批号或批次号查找具体证书。

搜索COA

已有该产品？

在文件库中查找您最近购买产品的文档。

访问文档库

Anne Santerre Henriksen et al.
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 37(9), 1653-1659 (2018-06-08)
Coagulase-negative staphylococci (CoNS) are a significant cause of bacteraemia, the treatment of which is becoming increasingly complex due to the emergence of multidrug-resistant strains. This study aimed to evaluate the in vitro activity of ceftobiprole, an advanced-generation cephalosporin, as compared
Impact of PBP4 Alterations on ?-Lactam Resistance and Ceftobiprole Non-Susceptibility Among Enterococcus faecalis Clinical Isolates
Lazzaro LM, Cassisi M, Stefani S, Campanile F
Frontiers in Cellular and Infection Microbiology, 11, 816657-816657 (2022)
Gunnar T R Hischebeth et al.
Diagnostic microbiology and infectious disease, 91(2), 175-178 (2018-02-18)
Antibiotic therapy is essential in foreign body associated infections. The treatment regime should aim at high tissue concentrations, high bioavailability, high biofilm penetration and good tolerance. We investigated whether the new cephalosporin ceftobiprole is active against clinical isolates from musculoskeletal

我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系客户支持