SML3647
Ulifloxacin
≥98% (HPLC)
别名:
6-Fluoro-1-methyl-4-oxo-7-(1-piperazinyl)-1H,4H-[1,3]thiazeto[3,2-a]quinoline-3-carboxylic acid, AF 3013, NAD 394, NM 394
质量水平
方案
≥98% (HPLC)
表单
powder
颜色
white to beige
溶解性
DMSO: 2 mg/mL, clear
储存温度
2-8°C
SMILES字符串
Fc1cc2c(cc1N4CCNCC4)N3C(SC3=C(C2=O)C(=O)O)C
InChI
1S/C16H16FN3O3S/c1-8-20-11-7-12(19-4-2-18-3-5-19)10(17)6-9(11)14(21)13(16(22)23)15(20)24-8/h6-8,18H,2-5H2,1H3,(H,22,23)
InChI key
SUXQDLLXIBLQHW-UHFFFAOYSA-N
相关类别
生化/生理作用
Orally available, broad-spectrum fluoroquinolone antibacterial agent that potently inhibits bacterial DNA gyrase and topoisomerase IV
Ulifloxacin is an orally available, broad-spectrum fluoroquinolone antibacterial agent. Ulifloxacin is an active metabolite of Prulifloxacin. It potently inhibits bacterial DNA gyrase and topoisomerase IV.
警示用语：
Warning
危险声明
危险分类
Lact. - Skin Irrit. 2 - STOT RE 2
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
此项目有
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
Susan J Keam et al.
Drugs, 64(19), 2221-2234 (2004-10-01)
Prulifloxacin, the prodrug of ulifloxacin, is a broad-spectrum oral fluoroquinolone antibacterial agent. After absorption, prulifloxacin is metabolised by esterases to ulifloxacin. The drug has a long elimination half-life, allowing once-daily administration. Ulifloxacin is generally more active in vitro than other
Valeria Tellone et al.
Drugs in R&D, 18(3), 237-245 (2018-08-29)
The antibacterial agent prulifloxacin, a prodrug of ulifloxacin, is indicated in the treatment of acute lower urinary tract infections, acute exacerbation of chronic bronchitis and acute bacterial rhinosinusitis. We aimed to provide new insights on the pharmacokinetics (PK) of ulifloxacin
Marcello Locatelli et al.
Journal of enzyme inhibition and medicinal chemistry, 31(1), 106-111 (2015-02-17)
A new and specific HPLC-DAD method for the direct determination of Prulifloxacin and its active metabolite, Ulifloxacin, in human plasma has been developed. Plasma samples were analysed after a simple solid phase extraction (SPE) clean-up using a new HILIC stationary
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