SML3647
Ulifloxacin
≥98% (HPLC)
别名:
6-Fluoro-1-methyl-4-oxo-7-(1-piperazinyl)-1H,4H-[1,3]thiazeto[3,2-a]quinoline-3-carboxylic acid, AF 3013, NAD 394, NM 394
登录 查看组织和合同定价。
选择尺寸
关于此项目
经验公式（希尔记法）:
C16H16FN3O3S
化学文摘社编号:
分子量:
349.38
UNSPSC Code:
51111800
NACRES:
NA.77
MDL number:
SMILES string
Fc1cc2c(cc1N4CCNCC4)N3C(SC3=C(C2=O)C(=O)O)C
InChI
1S/C16H16FN3O3S/c1-8-20-11-7-12(19-4-2-18-3-5-19)10(17)6-9(11)14(21)13(16(22)23)15(20)24-8/h6-8,18H,2-5H2,1H3,(H,22,23)
InChI key
SUXQDLLXIBLQHW-UHFFFAOYSA-N
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
2-8°C
Quality Level
Biochem/physiol Actions
Orally available, broad-spectrum fluoroquinolone antibacterial agent that potently inhibits bacterial DNA gyrase and topoisomerase IV
Ulifloxacin is an orally available, broad-spectrum fluoroquinolone antibacterial agent. Ulifloxacin is an active metabolite of Prulifloxacin. It potently inhibits bacterial DNA gyrase and topoisomerase IV.
signalword
Warning
hcodes
Hazard Classifications
Lact. - Skin Irrit. 2 - STOT RE 2
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Susan J Keam et al.
Drugs, 64(19), 2221-2234 (2004-10-01)
Prulifloxacin, the prodrug of ulifloxacin, is a broad-spectrum oral fluoroquinolone antibacterial agent. After absorption, prulifloxacin is metabolised by esterases to ulifloxacin. The drug has a long elimination half-life, allowing once-daily administration. Ulifloxacin is generally more active in vitro than other
Valeria Tellone et al.
Drugs in R&D, 18(3), 237-245 (2018-08-29)
The antibacterial agent prulifloxacin, a prodrug of ulifloxacin, is indicated in the treatment of acute lower urinary tract infections, acute exacerbation of chronic bronchitis and acute bacterial rhinosinusitis. We aimed to provide new insights on the pharmacokinetics (PK) of ulifloxacin
Marcello Locatelli et al.
Journal of enzyme inhibition and medicinal chemistry, 31(1), 106-111 (2015-02-17)
A new and specific HPLC-DAD method for the direct determination of Prulifloxacin and its active metabolite, Ulifloxacin, in human plasma has been developed. Plasma samples were analysed after a simple solid phase extraction (SPE) clean-up using a new HILIC stationary
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持