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Merck
CN

SML3713

HM-chromanone

≥98% (HPLC)

别名:

(3E)-2,3-Dihydro-5-hydroxy-3-[(2-hydroxyphenyl)methylene]-7-methoxy-4H-1-benzopyran-4-one, (E)-5-hydroxy-7-methoxy-3-(20-hydroxybenzyl)-4-chromanone, Portulacanone D

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关于此项目

经验公式(希尔记法):
C17H14O5
化学文摘社编号:
分子量:
298.29
NACRES:
NA.77
UNSPSC Code:
12352200
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assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

2-8°C

Quality Level

Biochem/physiol Actions

Sappanine-type homoisoflavonoid, isolated from Portulaca oleracea (purslane) that exhibits anti-diabetic effects.

HM-chromanone is a sappanine-type homoisoflavonoid, isolated from Portulaca oleracea (purslane). HM-chromanone exhibits anti-diabetic effects and inhibits adipogenesis by regulating AMPK activity in adipocytes. HM-chromanone potently activates AMPK in hepatocytes, thus suppressing hepatic glucose production. HM-chromanone does not display significant toxicity.

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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HM-Chromanone Ameliorates Hyperglycemia and Dyslipidemia in Type 2 Diabetic Mice
Nutrients, 14(9), 1951-1951 (2022)
HM-Chromanone Isolated from Portulaca oleracea L. Protects INS-1 Pancreatic ? Cells against Glucotoxicity-Induced Apoptosis
Nutrients, 11(2), 404-404 (2019)
HM-chromanone suppresses hepatic glucose production via activation of AMP-activated protein kinase in HepG2 cell
European Journal of Pharmacology, 928, 175108-175108 (2022)

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