SML3739
AZ Dyrk1B 33
≥98% (HPLC)
别名:
3-(2-Methyl-4-pyrimidinyl)-1-(phenylmethyl)-1H-pyrrolo[2,3-c]pyridine, AZ-Dyrk1B-33
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关于此项目
经验公式（希尔记法）:
C19H16N4
化学文摘社编号:
分子量:
300.36
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
Quality Segment
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
2-8°C
Biochem/physiol Actions
Potent and selective Dyrk1B kinase inhibitor that increased the number of incretin-expressing cells in diabetic mice.
AZ Dyrk1B 33 is a potent and selective Dyrk1B kinase (dual-specificity tyrosine phosphorylation-regulated kinase 1B) inhibitor. AZ Dyrk1B 33 potently increases the numbers of neurogenin 3-expressing enteroendocrine progenitors, Gip-expressing K-cells, and Glp-1-expressing L-cells in zebrafish and diabetic mice. It decreases glucose levels in both larval and juvenile zebrafish.
AZ Dyrk1B 33 is a potent and selective Dyrk1B kinase (dual-specificity tyrosine phosphorylation-regulated kinase 1B) inhibitor. AZ Dyrk1B 33 potently increases the numbers of neurogenin 3-expressing enteroendocrine progenitors, Gip-expressing K-cells, and Glp-1-expressing L-cells in zebrafish and diabetic mice. It decreases glucose levels in both larval and juvenile zebrafish.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable