SML3769
CWI1-2 Hydrochloride
≥98% (HPLC)
别名:
N,N′,N′′-Tris(5-chloro-2-hydroxybenzylideneamino)guanidine hydrochloride
质量水平
方案
≥98% (HPLC)
表单
powder
储存条件
desiccated
颜色
white to beige
溶解性
DMSO: 2 mg/mL, clear
储存温度
2-8°C
SMILES字符串
ClC1=CC=C(O)C(/C=N/N=C(N/N=C/C2=C(O)C=CC(Cl)=C2)N/N=C/C3=C(O)C=CC(Cl)=C3)=C1.Cl
InChI key
UXAOLDYLYMMMRC-SXOKSYETSA-N
相关类别
生化/生理作用
CWI1-2 is a cell penetrant, potent and selective inhibitor of an m6A reader IGF2BP2 (Insulin-like growth factor 2 mRNA-binding protein 2). CWI1-2 potently inhibits IGF2BP2 interaction with N6-Methyladenosine (m6A) modified target transcripts. CWI1-2 exhibits potent anti-leukemia efficacy in vitro and in vivo.
Cell penetrant, potent and selective inhibitor of an m6A reader IGF2BP2
免责声明
Hygroscopic
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
此项目有
Synthesis of Novel N,N?,N?-Tris[aryl(hetaryl)-methylideneamino]guanidine Derivatives as Efficient and Selective Colorimetric Sensors for Fluoride Ion
Russian Journal of Organic chemistry (2019)
The m6A reader IGF2BP2 regulates glutamine metabolism and represents a therapeutic target in acute myeloid leukemia
Cancer Cell, 40(12), 1566-1582 (2022)
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持