SML3790
MS67N
≥98% (HPLC)
别名:
N-(2′-Fluoro-5′-((2-(((S)-1-((2R,4S)-4-hydroxy-2-(((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)amino)-2-oxoethyl)carbamoyl)-4-((3S,5R)-3,4,5-trimethylpiperazin-1-yl)-[1,1′-biphenyl]-3-yl)-6-oxo-4-(trifluoromethyl)-1,6-dihydropyridine-3-carboxamide
相关类别
生化/生理作用
MS67N is a diastereoisomer of WDR5 degrader MS67 that serves as negative control.
Negative control for WDR5 degrader MS67
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
A selective WDR5 degrader inhibits acute myeloid leukemia in patient-derived mouse models
Science Translational Medicine, 13(613) (2021)
Human WDR5 promotes breast cancer growth and metastasis via KMT2-independent translation regulation.
Wesley L Cai et al.
eLife, 11 (2022-09-01)
Metastatic breast cancer remains a major cause of cancer-related deaths in women, and there are few effective therapies against this advanced disease. Emerging evidence suggests that key steps of tumor progression and metastasis are controlled by reversible epigenetic mechanisms. Using
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持