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Merck
CN

SML3806

Cefditoren sodium

≥95% (HPLC)

别名:

(6R,7R)-7-[[(2Z)-2-(2-Amino-4-thiazolyl)-2-(methoxyimino)acetyl]amino]-3-[(1Z)-2-(4-methyl-5-thiazolyl)ethenyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid sodium salt, Cefditoren Acid Sodium Salt, ME 1206 sodium salt

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经验公式(希尔记法):
C19H17N6NaO5S3
化学文摘社编号:
分子量:
528.56
UNSPSC Code:
12352200
NACRES:
NA.21
MDL number:
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产品名称

Cefditoren sodium, ≥95% (HPLC)

assay

≥95% (HPLC)

form

powder

storage condition

desiccated

color

white to beige

solubility

H2O: 2 mg/mL, clear (Warmed)

storage temp.

-10 to -25°C

Quality Level

Biochem/physiol Actions

Cefditoren sodium is orally available, broad spectrum third-generation cephalosporin antibiotic. Cefditoren sodium is active against both gram-negative and gram-positive bacteria. It is commonly used for treatment of chronic bronchitis, community-acquired pneumonia, pharyngitis/tonsillitis, and uncomplicated skin and skin-structure infections.
Orally available, broad spectrum third-generation cephalosporin antibiotic

Disclaimer

Hygroscopic

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Pharmacokinetic changes of cefdinir and cefditoren and its molecular mechanisms in acute kidney injury in rats
The Journal of Pharmacy and Pharmacology, 70(11), 1503-1512 (2018)
Enhanced in vivo activity of cefditoren in pre-immunized mice against penicillin-resistant S. pneumoniae (serotypes 6B, 19F and 23F) in a sepsis model
PLoS ONE, 5(8) (2010)
A Tamura et al.
Antimicrobial agents and chemotherapy, 32(9), 1421-1426 (1988-09-01)
ME1207 (pivaloyloxymethyl ester of ME1206) is a new oral cephalosporin. ME1206 is (6R,7R)-7-[(Z)-2-(2-aminothiazol-4-yl)-2-(methoxyimino)- acetamido]-3-[(Z)-2-(4-methylthiazol-5-yl)-ethyl]-cephem-4-carboxy lic acid. The susceptibilities of about 1,600 clinical isolates to ME1206 were determined by the agar dilution method. ME1206 showed a broad spectrum of activity against

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