SML3808
Firategrast
≥98% (HPLC)
别名:
SB 683699, T 0047, T-0047, (αS)-α-[(2,6-Difluorobenzoyl)amino]-4′-(ethoxymethyl)-2′,6′-dimethoxy[1,1′-biphenyl]-4-propanoic acid, (S)-2-(2,6-Difluorobenzamido)-3-(4′-(ethoxymethyl)-2′,6′-dimethoxy-[1,1′-biphenyl]-4-yl)propanoic acid, SB-683699
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关于此项目
Assay:
≥98% (HPLC)
Form:
powder
Quality Segment
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
2-8°C
Biochem/physiol Actions
Firategrast is an orally available, potent and selective antagonist of α4β1/α4β7 integrins. Firategrast inhibits α4β1/α4β7 integrin-mediated transferring of lymphocytes into the central nervous system (CNS). In phase II trial it demonstrated a reduction of new contrast enhancing MRI lesions in patients with relapsing remitting MS.
Orally available, potent and selective antagonist of α4β1/α4β7 integrins
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable