SML3837
WEHI-9625
≥98% (HPLC)
别名:
7-(2-(4-methoxybenzoyl)phenyl)-N-(4-methylbenzyl)-4H-thieno[3,2-c]thiochromene-2-carboxamide 5,5-dioxide, WEHI 9625
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关于此项目
经验公式（希尔记法）:
C34H27NO5S2
化学文摘社编号:
分子量:
593.71
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
Quality Level
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
-10 to -25°C
Biochem/physiol Actions
VDAC2 ligand that enhances VDAC2:BAK interaction and selectively blocks murine BAK-mediated apoptosis.
WEHI-9625 is a VDAC2 ligand that enhances VDAC2:BAK interaction and selectively blocks murine BAK-mediated apoptosis in early stages. WEHI-9625 preserves cellular function and long-term clonogenic potential before apoptosis induced mitochondrial damage. WEHI-9625 is inactive against both human BAK (hBAK) and BAX.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Mark F van Delft et al.
Nature chemical biology, 15(11), 1057-1066 (2019-10-09)
Activating the intrinsic apoptosis pathway with small molecules is now a clinically validated approach to cancer therapy. In contrast, blocking apoptosis to prevent the death of healthy cells in disease settings has not been achieved. Caspases have been favored, but
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| SML3837-10MG | 04065270396549 |