SML3859
Cefacetrile
≥98% (HPLC)
别名:
(6R,7R)-3-(Acetoxymethyl)-7-(cyanoacetamido)-8-oxo-5-thia-1azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-Cyanoacetamidocephalosporanic acid, Cephacetrile
生化/生理作用
Broad-spectrum first generation cephalosporin antibiotic against gram-positive and gram-negative bacteria.
Cefacetrile (cephacetrile) is a broad-spectrum first generation cephalosporin antibiotic against gram-positive and gram-negative bacteria. Cefacetrile inhibits the third and last stage of bacterial cell wall synthesis by binding to specific penicillin-binding proteins (PBPs) located inside the bacterial cell wall. Cell lysis is then mediated by bacterial cell wall autolytic enzymes such as autolysins.
Cefacetrile (cephacetrile) is a broad-spectrum first generation cephalosporin antibiotic against gram-positive and gram-negative bacteria. Cefacetrile inhibits the third and last stage of bacterial cell wall synthesis by binding to specific penicillin-binding proteins (PBPs) located inside the bacterial cell wall. Cell lysis is then mediated by bacterial cell wall autolytic enzymes such as autolysins.
警示用语：
Danger
危险声明
危险分类
Resp. Sens. 1 - Skin Sens. 1
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
此项目有
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
Comparative evaluation of cephacetrile in experimentally induced bovine mastitis.
J Schluep et al.
Zentralblatt fur Veterinarmedizin. Reihe B. Journal of veterinary medicine. Series B, 26(4), 304-324 (1979-05-01)
M G Bals et al.
Infection, 3(3), 161-164 (1975-01-01)
Cephacetrile, a parenteral cephalosporin, was evaluated for in vitro antibacterial activity, clinical pharmacology and effectiveness in the treatment of severe infections. The antibacterial activity against 187 isolates was determined by an agar-dilution technique. The MICs were 0.06 to 0.5 mug/ml
P Bianchi et al.
Bollettino dell'Istituto sieroterapico milanese, 58(6), 488-495 (1980-01-31)
6-cephalosporins (cephalothin, cephradine, cephacetrile, cefaclor, cefuroxime, cefotaxime) has been tested in vitro against 212 gram negative bacteria and 60 Staphylococci. Cefuroxime and especially Cefotaxime showed the highest activity against the gram negative bacteria, with a very low MIC. Cefotaxime also
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