SML3866
SCR2682
≥98% (HPLC)
别名:
N-[4-(2-Bromo-6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)-2,6-dimethylphenyl]-3,3-dimethylbutanamide
生化/生理作用
Potent and selective opener of neuronal Kv7/KCNQ/M-channels that activates the native M-current in rat hippocampal or cortical neurons
SCR2682 is potent and selective opener of neuronal Kv7/KCNQ/M-channels that activates the native M-current in rat hippocampal or cortical neurons. It reverses epileptic seizures in rodents. SCR2682 relieves mechanical allodynia and thermal hyperalgesia in rat models of pain.
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
此项目有
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
Attenuation of Epileptogenesis and Cognitive Deficits by a Selective and Potent Kv7 Channel Opener in Rodent Models of Seizures
Journal of Pharmacology and Experimental Therapeutics, 384(2), 315-325 (2023)
Electrophysiological and pharmacological characterization of a novel and potent neuronal Kv7 channel opener SCR2682 for antiepilepsy
Faseb Journal, 33(8), 9154-9166 (2019)
Activation of Neuronal Voltage-Gated Potassium Kv7/KCNQ/M-Current by a Novel Channel Opener SCR2682 for Alleviation of Chronic Pain
Journal of Pharmacology and Experimental Therapeutics, 377(1), 20-28 (2021)
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持