SML3869
Avibactam Sodium
≥98% (HPLC), β-lactamase inhibitor, powder
别名:
(2S,5R)-7-Oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide monosodium salt, AVE1330A sodium salt, NXL-104 sodium salt, Sulfuric acid mono[(1R,2S,5R)-2-(aminocarbonyl)-7-oxo-1,6-diazabicyclo[3.2.1]oct-6-yl] ester sodium salt
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关于此项目
经验公式（希尔记法）:
C7H10N3NaO6S
化学文摘社编号:
分子量:
287.23
UNSPSC Code:
51111800
NACRES:
NA.21
MDL number:
产品名称
Avibactam Sodium, ≥98% (HPLC)
SMILES string
[Na+].[S](=O)(=O)([O-])ON1[C@H]2CN([C@@H](CC2)C(=O)N)C1=O
InChI key
RTCIKUMODPANKX-JBUOLDKXSA-M
assay
≥98% (HPLC)
form
powder
storage condition
desiccated
color
white to beige
solubility
H2O: 2 mg/mL, clear
storage temp.
-10 to -25°C
Quality Level
Biochem/physiol Actions
Avibactam is a reversible non-β-lactam β-lactamase inhibitor with IC50 values of 5 nM for CTX-M-15, 8nM for TEM-1, and 80 nM for P99 β-lactamase enzymes.
Reversible non-β-lactam, β-lactamase inhibitor
Disclaimer
Hygroscopic
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Avibactam is a covalent, reversible, non-?-lactam ?-lactamase inhibitor
Proceedings of the National Academy of Sciences of the USA, 109(29), 11663-11668 (2012)
Efficacies of ceftazidime-avibactam and ceftazidime against Pseudomonas aeruginosa in a murine lung infection model
Antimicrobial Agents and Chemotherapy, 58(3), 1365-1371 (2014)
Carbapenemase Inhibitors: Updates on Developments in 2021
Journal of clinical medicine research, 14(7), 251-259 (2022)
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