SMILES string
O=C(C1=CC(CC2=NNC(C3=C2C=C(C=C3)C#CC)=O)=CC=C1F)N4CCN(CC4)C5=NC=C(C=C5)C#N
assay
≥94% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
2-8°C
Quality Level
Biochem/physiol Actions
Cell penetrant, potent, and selective inhibitor of PARP7 that inhibits auto-MARylation and induced IFN-β in mouse colon carcinoma.
KMR-206 is a cell penetrant, potent, and selective inhibitor of PARP7 that inhibits auto-MARylation and induced IFN-β in mouse colon carcinoma (CT-26) cells. Also increased PARP7 protein levels in CT-26 cells.
KMR-206 is a cell penetrant, potent, and selective inhibitor of PARP7 that inhibits auto-MARylation and induced IFN-β in mouse colon carcinoma (CT-26) cells. Also increased PARP7 protein levels in CT-26 cells.
Z G Jia et al.
Zhonghua zhong liu za zhi [Chinese journal of oncology], 9(2), 124-126 (1987-03-01)
CT guided percutaneous fine needle aspiration cytodiagnosis was performed on 30 patients with pancreatic and periampullary tumors in China-Japan Friendship Hospital from November 1984 to January 1986. In our series, 9 pancreatic head cancers, 4 pancreatic body and tail cancers
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