SML3887
DS-5272
≥98% (HPLC)
别名:
DS 5272, [(2S,4R)-1-[[(5R,6S)-5-(4-Chloro-3-fluorophenyl)-6-(6-chloro-3-pyridinyl)-5,6-dihydro-6-methyl-3-(1-methylethyl)imidazo[2,1-b]thiazol-2-yl]carbonyl]-4-fluoro-2-pyrrolidinyl][(6R)-6-ethyl-4,7-diazaspiro[2.5]oct-7-yl]methanone
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关于此项目
Assay:
≥98% (HPLC)
Form:
powder
Quality Segment
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
-10 to -25°C
Biochem/physiol Actions
Orally active and potent inhibitor of p53-MDM2 interaction.
DS-5272 is an orally active and potent inhibitor of p53-MDM2 interaction that exhibits efficacy against number of tumors including acute myeloid leukemia (AML). DS-5272 induces an immune-inflammatory response in MLL-AF9 cells.
DS-5272 is an orally active and potent inhibitor of p53-MDM2 interaction that exhibits efficacy against number of tumors including acute myeloid leukemia (AML). DS-5272 induces an immune-inflammatory response in MLL-AF9 cells.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable