SML3888
Dynapyrazole Compound 20
≥98% (HPLC)
别名:
6-(3-bromophenoxy)-2- [1-(4-chlorophenyl) cyclopropyl]-7-oxo-4H-pyrazolo[1,5-a]pyrimidine-3-carbonitrile, Compound 20
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关于此项目
经验公式（希尔记法）:
C22H14BrClN4O2
分子量:
481.73
NACRES:
NA.77
UNSPSC Code:
12352200
Assay:
≥98% (HPLC)
Form:
powder
Quality Segment
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
-10 to -25°C
Biochem/physiol Actions
Dynapyrazole Compound 20 is a potent and selective inhibitor of cytoplasmic S. cerevisiae dynein, an AAA (ATPase associated with diverse cellular activities), which engages the regulatory ATPase sites in the AAA3 and AAA4 domains disrupting allosteric communication across the AAA ring. Ddynapyrazole Compound 20 inhibits dynein’s basal ATPase activity. Also, it inhibits dynein motility by reducing the protein’s ability to bind microtubules.
Potent and selective inhibitor of cytoplasmic S. cerevisiae dynein
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable