SML3907
CNS-11g
≥98% (HPLC)
别名:
2-(4-benzyl-1-oxo-2(1H)-phthalazinyl)-N-(2,6-dimethylphenyl)acetamide, N-(2,6-Dimethylphenyl)-1-oxo-4-(phenylmethyl)-2(1H)-phthalazineacetamide
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关于此项目
经验公式（希尔记法）:
C25H23N3O2
化学文摘社编号:
分子量:
397.47
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
Quality Segment
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear (Warmed)
storage temp.
2-8°C
Biochem/physiol Actions
Brain tissue penetrant alpha-synuclein ligand that potently disaggregate alpha-synuclein fibrils in vitro and in vivo models.
CNS-11g is brain tissue penetrant alpha-synuclein ligand that potently disaggregate alpha-synuclein fibrils in vitro and in vivo models. CNS-11g inhibits intracellular seeding of a-synuclein fibrils in biosensor cells-HEK293T cells and mitigate a-synuclein cytotoxicity in Neuro-2a (N2a) neuronal cells. C-11g reduces number of a-synuclein aggregates in C. elegans model.
CNS-11g is brain tissue penetrant alpha-synuclein ligand that potently disaggregate alpha-synuclein fibrils in vitro and in vivo models. CNS-11g inhibits intracellular seeding of a-synuclein fibrils in biosensor cells-HEK293T cells and mitigate a-synuclein cytotoxicity in Neuro-2a (N2a) neuronal cells. C-11g reduces number of a-synuclein aggregates in C. elegans model.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable