SML3932
DC-Y13-27
≥98% (HPLC)
别名:
(E)-2-cyano-3-(5-(3-hydroxyphenyl)thiophen-2-yl)acrylamide
InChI key
FCXTXGWIQGHISV-JXMROGBWSA-N
SMILES string
NC(/C(C#N)=C/C1=CC=C(C2=CC=CC(O)=C2)S1)=O
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 30 mg/mL, clear
storage temp.
room temp
Quality Level
Biochem/physiol Actions
Cell penetrant and specific inhibitor of an m6A reader YTHDF2.
DC-Y13-27 is a cell penetrant and specific inhibitor of an m6A reader YTHDF2 that overcomes MDSC(myeloid-derived suppressor cell)-induced immunosuppression and enhances combined IR and/or anti-PD-L1 treatment.
DC-Y13-27 is a cell penetrant and specific inhibitor of an m6A reader YTHDF2 that overcomes MDSC(myeloid-derived suppressor cell)-induced immunosuppression and enhances combined IR and/or anti-PD-L1 treatment.
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Liangliang Wang et al.
Cancer cell, 41(7), 1294-1308 (2023-05-27)
RNA N6-methyladenosine (m6A) modification is implicated in cancer progression. However, the impact of m6A on the antitumor effects of radiotherapy and the related mechanisms are unknown. Here we show that ionizing radiation (IR) induces immunosuppressive myeloid-derived suppressor cell (MDSC) expansion
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持