SML3937
GPX4-Activator-1d4 Hydrochloride
≥98% (HPLC)
别名:
N-(2-Aminoethyl)-4-(3-cyclopentylthioureido)-benzenesulfonamide hydrochloride, N-(2-Aminoethyl)-4-[[(cyclopentylamino)thioxomethyl]amino]-benzenesulfonamide hydrochloride, PKUMDL-LC-101-D04
质量水平
方案
≥98% (HPLC)
表单
powder
储存条件
desiccated
颜色
white to beige
溶解性
H2O: 2 mg/mL, clear
储存温度
-10 to -25°C
SMILES字符串
S=C(NC1=CC=C(C=C1)S(NCCN)(=O)=O)NC2CCCC2.Cl
InChI key
FELDRJSFLBINQS-UHFFFAOYSA-N
生化/生理作用
Cell penetrant, potent and elective allosteric activator of glutathione peroxidase 4 (GPX4) that potently inhibit ferroptosis.
GPX4-Activator-1d4 HCl is a cell penetrant, potent and elective allosteric activator of glutathione peroxidase 4 (GPX4) that potently inhibit ferroptosis. It significantly increases GPX4 activity to 150% at 20 μM in the cell-free assay and 61 μM in cell extracts. GPX4-Activator-1d4 suppresses ferroptosis and inflammation in HT-1080 fibrosarcoma cells.
GPX4-Activator-1d4 HCl is a cell penetrant, potent and elective allosteric activator of glutathione peroxidase 4 (GPX4) that potently inhibit ferroptosis. It significantly increases GPX4 activity to 150% at 20 μM in the cell-free assay and 61 μM in cell extracts. GPX4-Activator-1d4 suppresses ferroptosis and inflammation in HT-1080 fibrosarcoma cells.
免责声明
Hygroscopic
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
此项目有
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持