SML3956
Cdk5i SC-FT trifluoroacetate
≥95% (HPLC)
别名:
Cdk5i-FT negative control trifluoroacetate, Cdk5i-FT scrambled control trifluoroacetate, FITC-Ahx-AFRSPCARIGYV-TAT trifluoroacetate, FITC-Ahx-AFRSPCARIGYV-YGRKKRRQRRR (FITC = fluorescein isothiocyanate; Ahx = 6-aminohexanoate) trifluoroacetate, FITC-Ahx-Cdk5i SC-TAT trifluoroacetate, SC-FT trifluoroacetate
质量水平
方案
≥95% (HPLC)
表单
(Powder or Lyophilized powder or film)
储存条件
desiccated
颜色
white to beige
储存温度
-10 to -25°C
生化/生理作用
Scrambled control for the brain-penetrant and selective cyclin-dependent kinase Cdk5/p25 complex inhibitor Cdk5i-FT.
Cdk5i SC-FT is the scrambled control for Cdk5i-FT, a brain-penetrant and selective cyclin-dependent kinase Cdk5/p25 complex inhibitor in vitro and in vivo.
Cdk5i SC-FT is the scrambled control for Cdk5i-FT, a brain-penetrant and selective cyclin-dependent kinase Cdk5/p25 complex inhibitor in vitro and in vivo.
免责声明
Hygroscopic
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
此项目有
Ping-Chieh Pao et al.
Proceedings of the National Academy of Sciences of the United States of America, 120(16), e2217864120-e2217864120 (2023-04-13)
Aberrant activity of cyclin-dependent kinase (Cdk5) has been implicated in various neurodegenerative diseases. This deleterious effect is mediated by pathological cleavage of the Cdk5 activator p35 into the truncated product p25, leading to prolonged Cdk5 activation and altered substrate specificity.
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