SML3956
Cdk5i SC-FT trifluoroacetate
≥95% (HPLC)
别名:
Cdk5i-FT negative control trifluoroacetate, Cdk5i-FT scrambled control trifluoroacetate, FITC-Ahx-AFRSPCARIGYV-TAT trifluoroacetate, FITC-Ahx-AFRSPCARIGYV-YGRKKRRQRRR (FITC = fluorescein isothiocyanate; Ahx = 6-aminohexanoate) trifluoroacetate, FITC-Ahx-Cdk5i SC-TAT trifluoroacetate, SC-FT trifluoroacetate
assay
≥95% (HPLC)
form
(Powder or Lyophilized powder or film)
storage condition
desiccated
color
white to beige
storage temp.
-10 to -25°C
Quality Level
Biochem/physiol Actions
Scrambled control for the brain-penetrant and selective cyclin-dependent kinase Cdk5/p25 complex inhibitor Cdk5i-FT.
Cdk5i SC-FT is the scrambled control for Cdk5i-FT, a brain-penetrant and selective cyclin-dependent kinase Cdk5/p25 complex inhibitor in vitro and in vivo.
Cdk5i SC-FT is the scrambled control for Cdk5i-FT, a brain-penetrant and selective cyclin-dependent kinase Cdk5/p25 complex inhibitor in vitro and in vivo.
Disclaimer
Hygroscopic
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Ping-Chieh Pao et al.
Proceedings of the National Academy of Sciences of the United States of America, 120(16), e2217864120-e2217864120 (2023-04-13)
Aberrant activity of cyclin-dependent kinase (Cdk5) has been implicated in various neurodegenerative diseases. This deleterious effect is mediated by pathological cleavage of the Cdk5 activator p35 into the truncated product p25, leading to prolonged Cdk5 activation and altered substrate specificity.
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