SML3957
OSS_128167
≥98% (HPLC)
别名:
5-[[3-[(2-Furanylcarbonyl)amino]benzoyl]amino]-2-hydroxybenzoic acid
登录 查看组织和合同定价。
选择尺寸
关于此项目
经验公式（希尔记法）:
C19H14N2O6
化学文摘社编号:
分子量:
366.32
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
SMILES string
N(c2cc(ccc2)C(=O)Nc3cc(c(cc3)O)C(=O)O)C(=O)c1[o]ccc1
InChI
1S/C19H14N2O6/c22-15-7-6-13(10-14(15)19(25)26)20-17(23)11-3-1-4-12(9-11)21-18(24)16-5-2-8-27-16/h1-10,22H,(H,20,23)(H,21,24)(H,25,26)
InChI key
HTJWLEGCECXGSQ-UHFFFAOYSA-N
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
-10 to -25°C
Quality Level
Biochem/physiol Actions
eCll penetrant, potent and selective inhibitor of SIRT6.
OSS_128167 is a cell penetrant, potent and selective inhibitor of SIRT6 (Sirtuin 6) that exhibits anti-cancer, anti-inflammatory, and anti-viral properties. OSS_128167 inhibits HBV transcription and replication through upregulating peroxisome proliferator-activated receptors α (PPARα) expression.
OSS_128167 is a cell penetrant, potent and selective inhibitor of SIRT6 (Sirtuin 6) that exhibits anti-cancer, anti-inflammatory, and anti-viral properties. OSS_128167 inhibits HBV transcription and replication through upregulating peroxisome proliferator-activated receptors α (PPARα) expression.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
SIRT6 Inhibitor, OSS_128167 Restricts Hepatitis B Virus Transcription and Replication Through Targeting Transcription Factor Peroxisome Proliferator-Activated Receptors ?
Frontiers in Pharmacology, 10, 1270-1270 (2019)
Discovery of novel and selective SIRT6 inhibitors
Journal of Medicinal Chemistry, 57(11), 4796-4804 (2014)
Diosgenin protects against podocyte injury in early phase of diabetic nephropathy through regulating SIRT6
Phytomedicine, 104, 154276-154276 (2022)
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持