Quality Segment
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear (warmed)
storage temp.
2-8°C
SMILES string
O=C1C2=C(C=C(C(OC)=C2O)OC)N(C)C3=C1C=CC=C3
Biochem/physiol Actions
Alkaloid isolated from leaves of Glycosmis bilocularis that exhibits strong anti-cancer, anti-bacterial, and anti-viral activities.
Arborinine is a quinoline alkaloid isolated from leaves of Glycosmis bilocularis that exhibits strong anti-cancer, anti-bacterial, and anti-viral activities. Arborinine is a broad-spectrum antiproliferative agent, which potently inhibits proliferation of numerous cancer cell lines including NCI-N87 (IC50 = 5.67 μM), BGC-823 (IC50 = 7.26 μM), MGC803 (IC50 = 4.75 μM) and more. It potently inhibits SKOV3 ovarian carcinoma cell proliferation and tumor growth. It also reduces migration and invasion of SKOV3 cancer cells. Arborinine reduces expression of histone demethylase LSD1, which leads to accumulation of H3K4m1.
Arborinine is a quinoline alkaloid isolated from leaves of Glycosmis bilocularis that exhibits strong anti-cancer, anti-bacterial, and anti-viral activities. Arborinine is a broad-spectrum antiproliferative agent, which potently inhibits proliferation of numerous cancer cell lines including NCI-N87 (IC50 = 5.67 μM), BGC-823 (IC50 = 7.26 μM), MGC803 (IC50 = 4.75 μM) and more. It potently inhibits SKOV3 ovarian carcinoma cell proliferation and tumor growth. It also reduces migration and invasion of SKOV3 cancer cells. Arborinine reduces expression of histone demethylase LSD1, which leads to accumulation of H3K4m1.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable