质量水平
方案
≥95% (HPLC)
表单
(Powder or Lyophilized powder or film)
颜色
white to off-white
储存温度
-10 to -25°C
SMILES字符串
O=C([C@H]1N(C([C@H](NC([C@H](CC(C)C)NC([C@H](CCCNC(N)=N)NC([C@@H](N2)[C@H](C)O)=O)=O)=O)CC3=CC=CC=C3)=O)CCC1)N[C@H](C(N[C@H](C(N[C@@H](CC(C)C)C(N[C@H](CC4=CC=CC=C4)C(N[C@H](C2=O)C)=O)=O)=O)CCCNC(N)=N)=O)C(C)C
生化/生理作用
In vivo active specific cyclic GMP-AMP synthase (cGAS) inhibitor that binds to DNA binding site of cGAS.
XQ2B, macrocyclic peptide derived from Gramicidin S, acts a specific cyclic GMP-AMP synthase (cGAS) inhibitor by directly targeting protein-DNA interface. XQ2B attenuates the host innate antiviral response.
XQ2B, macrocyclic peptide derived from Gramicidin S, acts a specific cyclic GMP-AMP synthase (cGAS) inhibitor by directly targeting protein-DNA interface. XQ2B attenuates the host innate antiviral response.
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
此项目有
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
Development of cyclopeptide inhibitors of cGAS targeting protein-DNA interaction and phase separation
Nature Communications, 14(1), 6132-6132 (2023)
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