Quality Segment
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
2-8°C
SMILES string
OC(CCC1=CC=CC2=C1B(OC2)O)=O
InChI
1S/C10H11BO4/c12-9(13)5-4-7-2-1-3-8-6-15-11(14)10(7)8/h1-3,14H,4-6H2,(H,12,13)
InChI key
CEVOKIPNIZQANN-UHFFFAOYSA-N
Biochem/physiol Actions
Boron containing antimalarial agent that targets Plasmodium falciparum CPSF3 (cleavage and polyadenylation specific factor 3).
AN3661 is a boron containing antimalarial agent that targets Plasmodium falciparum CPSF3 (cleavage and polyadenylation specific factor 3). AN3661potently inhibits Plasmodium falciparum laboratory-adapted strains (mean IC50=32 nM). Also, AN3661 inhibits T. gondii growth in human cells at low micromolar concentrations.
AN3661 is a boron containing antimalarial agent that targets Plasmodium falciparum CPSF3 (cleavage and polyadenylation specific factor 3). AN3661potently inhibits Plasmodium falciparum laboratory-adapted strains (mean IC50=32 nM). Also, AN3661 inhibits T. gondii growth in human cells at low micromolar concentrations.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable