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Merck
CN

SML4104

Tomatine

≥95% (HPLC)

别名:

(3β,5α,22β,25S)-Spirosolan-3-yl O-β-D-glucopyranosyl-(1→2)-O-[β-D-xylopyranosyl-(1→3)]-O-β-D-glucopyranosyl-(1→4)-β-D-galactopyranoside, Lycopersicin, NSC 234440, NSC 9223, Spirosolane, α-Tomatine, alpha-tomatine

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关于此项目

经验公式(希尔记法):
C50H83NO21
化学文摘社编号:
分子量:
1034.19
NACRES:
NA.21
Assay:
≥95% (HPLC)
Form:
powder
Quality level:
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biological source

tomato

Quality Level

assay

≥95% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear (warmed)

storage temp.

-10 to -25°C

SMILES string

N1[C@]2(O[C@@H]3[C@@H]([C@@]4([C@H]([C@H]5[C@@H]([C@@]6([C@H](C[C@H](CC6)O[C@@H]7O[C@@H]([C@@H]([C@@H]([C@H]7O)O)O[C@@H]8O[C@@H]([C@H]([C@@H]([C@H]8O[C@@H]%10O[C@@H]([C@H]([C@@H]([C@H]%10O)O)O)CO)O[C@@H]9OC[C@H]([C@@H]([C@H]9O)O)O)O)CO)CO)CC5)C)CC4)C3)C)[, C[C@@H]1[C@@]2(O[C@]3([H])[C@@]1([H])[C@]4(CC[C@]5([H])[C@@]6([C@@](C[C@@H](O[C@@H]7O[C@@H]([C@H](O[C@@H]8O[C@H](CO)[C@@H](O)[C@H](O[C@@H]9OC[C@@H](O)[C@H](O)[C@H]9O)[C@H]8O[C@H]%10[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O%10)[C@@H]([C@H]7O)O)CO)CC6)([H])CC[C@

InChI key

REJLGAUYTKNVJM-SGXCCWNXSA-N

Biochem/physiol Actions

Phytochemical from tomatoes; protects the plant from microbes; induces apoptosis in cancer cell lines.
Tomatine (Lycopersicin) is a natural glycoalkaloid from tomatoes that exhibits fungicidal, antimicrobial, and insecticidal properties. Tomatine induces apoptosis in cancer cell lines.


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hcodes

Hazard Classifications

Acute Tox. 4 Oral

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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Cesar Echeverría et al.
Frontiers in pharmacology, 13, 1003264-1003264 (2022-09-27)
Background: There is abundant ethnopharmacological evidence the uses of regarding Solanum species as antitumor and anticancer agents. Glycoalkaloids are among the molecules with antiproliferative activity reported in these species. Purpose: To evaluate the anticancer effect of the Solanum glycoalkaloid tomatine
Shin-Ichi Ito et al.
FEBS letters, 581(17), 3217-3222 (2007-06-26)
The tomato saponin alpha-tomatine has been proposed to kill sensitive cells by binding to cell membranes followed by leakage of cell components. However, details of the modes of action of the compound on fungal cells are poorly understood. In the



全球贸易项目编号

货号GTIN
SML4104-5MG04065272156578
SML4104-25MG04065272156561