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经验公式(希尔记法):
C27H31N5O3 · xC2HF3O2
化学文摘社编号:
分子量:
473.57 (free base basis)
MDL number:
NACRES:
NA.28
Assay:
≥95% (HPLC)
Form:
powder
Storage condition:
desiccated
Quality Segment
assay
≥95% (HPLC)
form
powder
storage condition
desiccated
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
2-8°C
SMILES string
OC(C=C1)=CC=C1CNC([C@@H](CCCNC(N)=N)NC(C(C2=CC=CC=C2)C3=CC=CC=C3)=O)=O
Biochem/physiol Actions
Potent and selective non-peptide neuropeptide Y receptor Y1 antagonist in vitro and in vivo.
BIBP3226 is a potent and selective non-peptide neuropeptide Y receptor Y1 antagonist (Ki = 7 nM against neuropeptide Y binding to receptor Y1) in vitro and in vivo. BIBP3226 selectively blocks Y1 receptor-mediated rabbit saphenous vein contraction (pA2 = 7.36), but not receptor Y2- or Y3-dependent biological effects.
BIBP3226 is a potent and selective non-peptide neuropeptide Y receptor Y1 antagonist (Ki = 7 nM against neuropeptide Y binding to receptor Y1) in vitro and in vivo. BIBP3226 selectively blocks Y1 receptor-mediated rabbit saphenous vein contraction (pA2 = 7.36), but not receptor Y2- or Y3-dependent biological effects.
Disclaimer
Hygroscopic
signalword
Warning
hcodes
Hazard Classifications
Skin Irrit. 2
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
