质量水平
方案
≥98% (HPLC)
表单
powder
颜色
white to beige
溶解性
DMSO: 2 mg/mL, clear
储存温度
-10 to -25°C
SMILES字符串
OC[C@@H]1NC2=CC=C(C3=C(F)C=CC=C3)C=C2[C@H]4[C@@H]1CCN4S(C5=CC=C(C)C=C5)(=O)=O
生化/生理作用
Cell penetrant and potent anti-CRISPR agent that inhibits SpCas9-DNA interaction.
BRD0539 is a cell penetrant and potent anti-CRISPR agent. BRD0539 is a reversible inhibitor of Streptococcus pyogenes Cas9 (SpCas9) that disrupt the SpCas9-DNA interaction. It potently inhibits SpCas9/PAM binding leading to a decrease in nuclease activity. BRD0539 is stable under physiological conditions.
BRD0539 is a cell penetrant and potent anti-CRISPR agent. BRD0539 is a reversible inhibitor of Streptococcus pyogenes Cas9 (SpCas9) that disrupt the SpCas9-DNA interaction. It potently inhibits SpCas9/PAM binding leading to a decrease in nuclease activity. BRD0539 is stable under physiological conditions.
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持