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Merck
CN

SML4136

BB2-50F

≥98% (HPLC)

别名:

3-Amino-N-(aminoiminomethyl)-6-(2-benzofuranyl)-5-(hexahydro-1H-azepin-1-yl)-2-pyrazinecarboxamide, 3-Amino-5-(azepan-1-yl)-6-(benzofuran-2-yl)-N-carbamimidoylpyrazine-2-carboxamide

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关于此项目

经验公式(希尔记法):
C20H23N7O2
化学文摘社编号:
分子量:
393.44
NACRES:
NA.21
Assay:
≥98% (HPLC)
Form:
powder
Quality level:
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Quality Level

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

2-8°C

SMILES string

NC(NC(C1=NC(C2=CC(C=CC=C3)=C3O2)=C(N4CCCCCC4)N=C1N)=O)=N

Biochem/physiol Actions

Cell penetrant, selective and potent multi-targeting bioenergetic inhibitor of succinate dehydrogenase and the F1Fo-ATP synthase in Mycobacterium tuberculosis; bactericidal antibiotic in MTB.
BB2-50F, an amiloride derivative, is a cell penetrant, selective and potent multi-targeting bioenergetic inhibitor of succinate dehydrogenase and the F1Fo-ATP synthase in Mycobacterium tuberculosis. BB2-50F act as fast acting bactericidal antibiotic in both replicating and nonreplicating cultures of M. tuberculosis (MIC = 2.6 µM in M. tuberculosis mc2 6230). BB2-50F is a potent inhibitor of bacterial motility.


存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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全球贸易项目编号

货号GTIN
SML4136-25MG04065272636520
SML4136-5MG04065272636537