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经验公式(希尔记法):
C17H18FN3O3·HCl · xH2O
化学文摘社编号:
分子量:
367.80 (anhydrous basis)
MDL number:
NACRES:
NA.21
Assay:
≥98% (HPLC)
Form:
powder
Storage condition:
desiccated
Quality Segment
assay
≥98% (HPLC)
form
powder
storage condition
desiccated
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
-10 to -25°C
SMILES string
O=C(C1=CN(C2CC2)C3=CC(N4CCNCC4)=C(C=C3C1=O)F)O.Cl.[xH2O]
Application
Ciprofloxacin hydrochloride hydrate is suitable for use in research to study antibiotic resistance mechanisms. It is also used to inhibit cell proliferation and to sensitize cells to TRAIL (TNF-related apoptosis-inducing ligand) -Induced apotosis.
Biochem/physiol Actions
Ciprofloxacinis a fluoroquinolone antibiotic with broad-spectrum activity, which killsbacteria by blocking DNA gyrase and type IV topoisomerase—critical enzymes forDNA replication and transcription—leading to cell death. It is effectiveagainst a broad array of both Gram-positive and Gram-negative bacteria, inaddition to Mycoplasmas. While the hydrochloride form of ciprofloxacin ishighly soluble in water, ciprofloxacin itself is only sparingly soluble inaqueous solutions.
Disclaimer
Hygroscopic Store with desiccant
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable