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Merck
CN

SML4150

Ciprofloxacin hydrochloride hydrate

≥98% (HPLC), powder

别名:

1-Cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid hydrochloride hydrate, 1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid monohydrochloride, monohydrate

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关于此项目

经验公式(希尔记法):
C17H18FN3O3·HCl · xH2O
化学文摘社编号:
分子量:
367.80 (anhydrous basis)
MDL number:
NACRES:
NA.21
Assay:
≥98% (HPLC)
Form:
powder
Storage condition:
desiccated
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Quality Segment

assay

≥98% (HPLC)

form

powder

storage condition

desiccated

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

-10 to -25°C

SMILES string

O=C(C1=CN(C2CC2)C3=CC(N4CCNCC4)=C(C=C3C1=O)F)O.Cl.[xH2O]

Application

Ciprofloxacin hydrochloride hydrate is suitable for use in research to study antibiotic resistance mechanisms. It is also used to inhibit cell proliferation and to sensitize cells to TRAIL (TNF-related apoptosis-inducing ligand) -Induced apotosis.

Biochem/physiol Actions

Ciprofloxacinis a fluoroquinolone antibiotic with broad-spectrum activity, which killsbacteria by blocking DNA gyrase and type IV topoisomerase—critical enzymes forDNA replication and transcription—leading to cell death. It is effectiveagainst a broad array of both Gram-positive and Gram-negative bacteria, inaddition to Mycoplasmas. While the hydrochloride form of ciprofloxacin ishighly soluble in water, ciprofloxacin itself is only sparingly soluble inaqueous solutions.

Disclaimer

Hygroscopic Store with desiccant


存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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