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Merck
CN

SML4198

Pogostone

≥98% (HPLC), powder, antimicrobial

别名:

4-Hydroxy-6-methyl-3-(4-methyl-1-oxopentyl)-2H-pyran-2-one; 4-Hydroxy-6-methyl-3-(4-methylpentanoyl)-2-pyrone, Dhelwangin

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关于此项目

经验公式(希尔记法):
C12H16O4
化学文摘社编号:
分子量:
224.25
MDL number:
NACRES:
NA.21
Assay:
≥98% (HPLC)
Form:
powder
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Quality Segment

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

2-8°C

SMILES string

CC(CCC(C1=C(C=C(OC1=O)C)O)=O)C

Application

Pogostone may be used:
  • to study its insecticidal activity against Spodoptera litura (Fabricius) and Spodoptera exigua (Hübner)
  • to study its effects on adipose tissue inflammation in vitro and in vivo
  • to study its effects on osteolytic bone metastases in mice and investigate the molecular mechanisms of pogostone against cancer-induced osteoclast formation and cancer cell proliferation or migration in vitro

Biochem/physiol Actions

Pogostone is an active ingredient isolated from the essential oil of Pogostemon cablin (patchouli oil) that exhibits various pharmacological properties, including anti-inflammatory and anti-cancer activities. Pogostone attenuates high-fat diet–induced nonalcoholic fatty liver disease (NAFLD) in mice through inhibition of NLRP3 inflammasome signaling.


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存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

No data available

flash_point_c

No data available



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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